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Cellosaurus CHL/IU KN63 (CVCL_UV18)

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Cell line name CHL/IU KN63
Synonyms KN63
Accession CVCL_UV18
Resource Identification Initiative To cite this cell line use: CHL/IU KN63 (RRID:CVCL_UV18)
Comments Characteristics: Designed to detect mutational events. The target gene is E.coli gpt that is present in a shuttle vector that can be rescued from the host cells (PubMed=9393622).
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4585 (CHL/IU)
Sex of cell Female
Age at sampling 1D
Category Spontaneously immortalized cell line
Publications

PubMed=9393622; DOI=10.1016/S1383-5718(97)00114-9
Toru Yamada, Kyoko Odawara, Fumio Kishida, Iwao Nakatsuka, Akira Yoshitake;
Development of a novel CHL/IU cell line with an incorporated gpt shuttle vector for concurrent analysis of gene mutations and chromosome aberrations.
Mutat. Res. 393:295-306(1997)

PubMed=11080658; DOI=10.1016/S1383-5718(00)00115-7
Toru Yamada, Kyoko Odawara, Hideo Kaneko;
Concurrent detection of gene mutations and chromosome aberrations induced by five chemicals in a CHL/IU cell line incorporating a gpt shuttle vector.
Mutat. Res. 471:29-36(2000)

Cross-references
Encyclopedic resources Wikidata; Q93450577
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number9