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Cellosaurus CHL CNM-4 (CVCL_UU76)

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Cell line name CHL CNM-4
Synonyms CNM-4
Accession CVCL_UU76
Resource Identification Initiative To cite this cell line use: CHL CNM-4 (RRID:CVCL_UU76)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7645; NAT1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P37039; Cavia porcellus Por.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_UU72 (CHL CR-68)
Children:
CVCL_UV07 (CHL 7M-102)CVCL_UV08 (CHL 7M-116)CVCL_UV09 (CHL 7M-124)
CVCL_UV10 (CHL 7M-126)CVCL_UV06 (CHL 7M-41)
Sex of cell Female
Age at sampling 1D
Category Spontaneously immortalized cell line
Publications

PubMed=8012961
Yoshiki Yanagawa, Minoru Sawada, Takeo Deguchi, Frank J. Gonzalez, Tetsuya Kamataki;
Stable expression of human CYP1A2 and N-acetyltransferases in Chinese hamster CHL cells: mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Cancer Res. 54:3422-3427(1994)

PubMed=7625840; DOI=10.1016/0003-9861(95)90016-0
Hisashi Hashimoto, Yoshiki Yanagawa, Minoru Sawada, Susumu Itoh, Takeo Deguchi, Tetsuya Kamataki;
Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
Arch. Biochem. Biophys. 320:323-329(1995)

Cross-references
Encyclopedic resources Wikidata; Q93450494
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number10