Cellosaurus cell line PC (CVCL

Cross-references
Cell line name	PC
Accession	CVCL_UU13
Resource Identification Initiative	To cite this cell line use: PC (RRID:CVCL_UU13)
Comments	From: Andren-Sandberg, Ake; Karolinska Institutet; Stockholm; Sweden.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp355Gly (c.1064A>G); Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=11787853).
Disease	Pancreatic carcinoma (NCIt: C207229)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=11787853; DOI=10.1007/s004280100474 Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch. 439:798-802(2001)
Cell line databases/resources	cancercelllines; CVCL_UU13
Encyclopedic resources	Wikidata; Q98128499
Polymorphism and mutation databases	IARC_TP53; 16743
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	10