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Cellosaurus 22B (CVCL_UT48)

[Text version]
Cell line name 22B
Synonyms 22-B; ESC22B
Accession CVCL_UT48
Resource Identification Initiative To cite this cell line use: 22B (RRID:CVCL_UT48)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Cell type: Stromal cell of endometrium; CL=CL_0002255.
Disease Endometriosis (NCIt: C3014)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_UT51 (22B-RFP)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=11696444; DOI=10.1016/S0002-9440(10)63030-1; PMCID=PMC1867070
Andreas Zeitvogel, Rudolf Baumann, Anna Starzinski-Powitz;
Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture model.
Am. J. Pathol. 159:1839-1852(2001)

PubMed=18001719; DOI=10.1016/j.fertnstert.2007.07.1358
Sakhila K. Banu, JeHoon Lee, Anna Starzinski-Powitz, Joe A. Arosh;
Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells.
Fertil. Steril. 90:972-987(2008)

PubMed=26199416; DOI=10.1073/pnas.1507931112; PMCID=PMC4534219
Joe A. Arosh, JeHoon Lee, Dakshnapriya Balasubbramanian, Jone A. Stanley, Charles R. Long, Mary W. Meagher, Kevin G. Osteen, Kaylon L. Bruner-Tran, Robert C. Burghardt, Anna Starzinski-Powitz, Sakhila K. Banu;
Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis.
Proc. Natl. Acad. Sci. U.S.A. 112:9716-9721(2015)

PubMed=32106286; DOI=10.1093/humrep/dez266; PMCID=PMC7048714
Andrea Romano, Sofia Xanthoulea, Elisa Giacomini, Bert Delvoux, Eugenia Alleva, Paola Vigano;
Endometriotic cell culture contamination and authenticity: a source of bias in in vitro research?
Hum. Reprod. 35:364-376(2020)

Cross-references
Encyclopedic resources Wikidata; Q93302224
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number8