Cellosaurus logo
expasy logo

Cellosaurus ICCSICi007-A (CVCL_UN02)

[Text version]
Cell line name ICCSICi007-A
Synonyms IC-AD2-F-iPS-4F-1
Accession CVCL_UN02
Resource Identification Initiative To cite this cell line use: ICCSICi007-A (RRID:CVCL_UN02)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Instituto Cajal; Madrid; Spain.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=31698192).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Induced pluripotent stem cell
STR profile Source(s): BNLC

Markers:
AmelogeninX
CSF1PO10,11
D5S81812
D7S82010,12
D13S3178,11
D16S5399,13
D21S1127,30
TH016,9.3
TPOX8
vWA16,19

Run an STR similarity search on this cell line
Web pages https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20iPS/Attachments/144/Caracteristicas%20-%20Documento%20de%20Depo%cc%81sito%20L%c3%adnea%20IC-AD2-F-iPS-4F-1-v2.pdf
https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20iPS/Attachments/144/Anexo%20-%20Anexos%20IC-AD2-F-iPS-4F-1-v3.pdf
Publications

PubMed=31698192; DOI=10.1016/j.scr.2019.101588
Diaz-Guerra E., Rodriguez-Traver E., Moreno-Jimenez E.P., de Rojas I., Rodriguez C., Orera M., Hernandez I., Ruiz A., Vicario-Abejon C.
An integration-free iPSC line, ICCSICi007-A, derived from a female Alzheimer's disease patient with the APOE-epsilon4/epsilon4 alleles.
Stem Cell Res. 41:101588-101588(2019)

Cross-references
Cell line databases/resources hPSCreg; ICCSICi007-A
Encyclopedic resources Wikidata; Q94313350
Entry history
Entry creation25-Feb-2019
Last entry update30-Jan-2024
Version number10