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Cellosaurus MM446 (CVCL_UM73)

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Cell line name MM446
Accession CVCL_UM73
Resource Identification Initiative To cite this cell line use: MM446 (RRID:CVCL_UM73)
Comments Caution: TP53 mutation indicated incorrectly as being in position Pro315 in PubMed=10070891.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro316Leu (c.943_944delCCinsTT); Zygosity=Unspecified (PubMed=10070891).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=9466661; DOI=10.1002/(SICI)1097-0215(19980209)75:4<590::AID-IJC16>3.0.CO;2-D
Christine A. White, Scott A. Thomson, Leanne T. Cooper, Peter M. van Endert, Robert Tampe, Barbara Coupar, Li Qiu, Peter G. Parsons, Denis J. Moss, Rajiv Khanna;
Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
Int. J. Cancer 75:590-595(1998)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Shuraila Francisca Zerp, Andrea van Elsas, Lucy T.C. Peltenburg, Peter I. Schrier;
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

Cross-references
Encyclopedic resources Wikidata; Q95990244
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number7