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Cellosaurus MM253c1-1T (CVCL_UM67)

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Cell line name MM253c1-1T
Accession CVCL_UM67
Resource Identification Initiative To cite this cell line use: MM253c1-1T (RRID:CVCL_UM67)
Comments Selected for resistance to: ChEBI; CHEBI_72568; MTIC (5-(3-methyl-1-triazeno)imidazole-4-carboxamide).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UM66 (MM253c1)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Publications

PubMed=7060019
Peter G. Parsons, Susan G. Smellie, Leanne E. Morrison, Ian P. Hayward;
Properties of human melanoma cells resistant to 5-(3',3'-dimethyl-1-triazeno)imidazole-4-carboxamide and other methylating agents.
Cancer Res. 42:1454-1461(1982)

PubMed=3756862
Kevin Maynard, Peter G. Parsons;
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UM67
Encyclopedic resources Wikidata; Q95990208
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8