Cellosaurus cell line TRNDi006-A (CVCL

Cellosaurus TRNDi006-A (CVCL_UL25)

Cross-references
Cell line name	TRNDi006-A
Synonyms	NCATS-CL7567; HT527A; GM29681; GM29681*B
Accession	CVCL_UL25
Secondary accession	CVCL_B5TN
Resource Identification Initiative	To cite this cell line use: TRNDi006-A (RRID:CVCL_UL25)
Comments	From: NIH-NCATS-TRND Branch; Rockville; USA. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:7632; NAGLU; Simple; p.Glu153Lys (c.457G>A); ClinVar=VCV001067431; Zygosity=Homozygous (PubMed=30933722).
Disease	Mucopolysaccharidosis type IIIB (NCIt: C84898) Sanfilippo syndrome type B (ORDO: Orphanet_79270)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0M01 (GM01426)
Sex of cell	Female
Age at sampling	1Y
Category	Induced pluripotent stem cell
Publications	PubMed=30933722; DOI=10.1016/j.scr.2019.101427; PMCID=PMC6559735 Wei Huang, Miao Xu, Rong Li, Amanda Baskfield, Jennifer Kouznetsova, Jeanette K. Beers, Ji-Zhong Zou, Cheng-Yu Liu, Wei Zheng; An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene. Stem Cell Res. 37:101427-101427(2019) PubMed=34411609; DOI=10.1016/j.yexcr.2021.112785; PMCID=PMC8440473 Wei Huang, Yu-Shan Cheng, Shu Yang, Manju Swaroop, Miao Xu, Wen-Wei Huang, Wei Zheng; Disease modeling for mucopolysaccharidosis type IIIB using patient derived induced pluripotent stem cells. Exp. Cell Res. 407:112785.1-112785.10(2021)
Cell line collections (Providers)	Coriell; GM29681
Cell line databases/resources	hPSCreg; TRNDi006-A
Encyclopedic resources	Wikidata; Q112129407 Wikidata; Q98133594
Entry history
Entry creation	25-Feb-2019
Last entry update	27-Nov-2025
Version number	11