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Cellosaurus BT206 (CVCL_UK64)

[Text version]
Cell line name BT206
Synonyms BT-206
Accession CVCL_UK64
Resource Identification Initiative To cite this cell line use: BT206 (RRID:CVCL_UK64)
Comments Group: Cancer stem cell line.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251
Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.-W., Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Lun X.-Q., Wells J.C., Grinshtein N., King J.C., Hao X.-G., Dang N.-H., Wang X.-L., Aman A., Uehling D., Datti A., Wrana J.L., Easaw J.C., Luchman H.A., Weiss S., Cairncross J.G., Kaplan D.R., Robbins S.M., Senger D.L.
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

PubMed=30153289; DOI=10.1371/journal.pone.0202860; PMCID=PMC6112648
Yuan A.L., Ricks C.B., Bohm A.K., Lun X.-Q., Maxwell L., Safdar S., Bukhari S., Gerber A., Sayeed W., Bering E.A., Pedersen H., Chan J.A.-W., Shen Y.-Q., Marra M.A., Kaplan D.R., Mason W.P., Goodman L.D., Ezhilarasan R., Kaufmann A.B., Cabral M., Robbins S.M., Senger D.L., Cahill D.P., Sulman E.P., Cairncross J.G., Blough M.D.
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
PLoS ONE 13:e0202860.1-e0202860.18(2018)

Cross-references
Encyclopedic resources Wikidata; Q93432843
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number9