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Cellosaurus BT108 (CVCL_UK59)

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Cell line name BT108
Accession CVCL_UK59
Resource Identification Initiative To cite this cell line use: BT108 (RRID:CVCL_UK59)
Comments Group: Cancer stem cell line.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Publications

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Xue-Qing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiao-Guang Hao, Ngoc-Ha Dang, Xiu-Ling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana ...Show all 18 authors... , Jacob Chirakkattu Easaw, Hema Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David Ross Kaplan, Stephen M. Robbins, Donna L. Senger; Show fewer authors
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

PubMed=30153289; DOI=10.1371/journal.pone.0202860; PMCID=PMC6112648
Alice L. Yuan, Christian B. Ricks, Alexandra K. Bohm, Xue-Qing Lun, Lori Maxwell, Shahana Safdar, Shazreh Bukhari, Amanda Gerber, Wajid Sayeed, Elizabeth Ann Bering, Haley Pedersen ...Show all 26 authors... , Jennifer Ai-Wen Chan, Yao-Qing Shen, Marco Antonio Marra, David Ross Kaplan, Warren P. Mason, Lindsey Dale Goodman, Ravesanker Ezhilarasan, Ascher B. Kaufmann, Matthew Cabral, Stephen M. Robbins, Donna L. Senger, Daniel P. Cahill, Erik P. Sulman, J. Gregory Cairncross, Michael D. Blough; Show fewer authors
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
PLoS ONE 13:e0202860.1-e0202860.18(2018)

Cross-references
Encyclopedic resources Wikidata; Q93432819
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number5