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Cellosaurus BT067 (CVCL_UK39)

[Text version]
Cell line name BT067
Synonyms BT67; BT-67
Accession CVCL_UK39
Resource Identification Initiative To cite this cell line use: BT067 (RRID:CVCL_UK39)
Comments Group: Cancer stem cell line.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3409

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S81812
D7S82010,12
D13S3179,11
D16S53912
TH017
TPOX8
vWA16,18

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Publications

PubMed=19544433; DOI=10.1002/stem.98
John J.P. Kelly, Owen D.M. Stechishin, Andrew Chojnacki, Xue-Qing Lun, Bei-Chen Sun, Donna L. Senger, Peter Forsyth, Roland N. Auer, Jeff F. Dunn, J. Gregory Cairncross, Ian Frederick Parney, Samuel Weiss;
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens.
Stem Cells 27:1722-1733(2009)

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251
Carlo Cusulin, Charles Chesnelong, Pinaki Bose, Misha Bilenky, Karen Kopciuk, Jennifer Ai-Wen Chan, J. Gregory Cairncross, Steven J.M. Jones, Marco Antonio Marra, Hema Artee Luchman, Samuel Weiss;
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Xue-Qing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiao-Guang Hao, Ngoc-Ha Dang, Xiu-Ling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana ...Show all 18 authors... , Jacob C. Easaw, Hema Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David Ross Kaplan, Stephen M. Robbins, Donna L. Senger; Show fewer authors
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

PubMed=30153289; DOI=10.1371/journal.pone.0202860; PMCID=PMC6112648
Alice L. Yuan, Christian B. Ricks, Alexandra K. Bohm, Xue-Qing Lun, Lori Maxwell, Shahana Safdar, Shazreh Bukhari, Amanda Gerber, Wajid Sayeed, Elizabeth Ann Bering, Haley Pedersen ...Show all 26 authors... , Jennifer Ai-Wen Chan, Yao-Qing Shen, Marco Antonio Marra, David Ross Kaplan, Warren P. Mason, Lindsey Dale Goodman, Ravesanker Ezhilarasan, Ascher B. Kaufmann, Matthew Cabral, Stephen M. Robbins, Donna L. Senger, Daniel P. Cahill, Erik P. Sulman, J. Gregory Cairncross, Michael D. Blough; Show fewer authors
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
PLoS ONE 13:e0202860.1-e0202860.18(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3409
Encyclopedic resources Wikidata; Q93432791
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number10