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Cellosaurus ICGi008-A (CVCL_UJ81)

[Text version]
Cell line name ICGi008-A
Synonyms m55Alz-9L
Accession CVCL_UJ81
Resource Identification Initiative To cite this cell line use: ICGi008-A (RRID:CVCL_UJ81)
Comments From: The Federal Research Center Institute of Cytology and Genetics; Novosibirsk; Russia.
Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 620; APP; Simple; p.Val717Ile (c.2149G>A); ClinVar=VCV000018088; Zygosity=Heterozygous (PubMed=30851551).
Disease Alzheimer's disease (NCIt: C2866)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UJ82 ! ICGi008-B
Sex of cell Male
Age at sampling 55Y
Category Induced pluripotent stem cell

PubMed=30851551; DOI=10.1016/j.scr.2019.101415
Grigor'eva E.V., Malankhanova T.B., Ustyantseva E.I., Minina J.M., Redina O.E., Morozov V.V., Shevela A.I., Zakian S.M., Medvedev S.P.
Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer's disease caused by London familial APP mutation (V717I).
Stem Cell Res. 36:101415-101415(2019)

Cell line databases/resources hPSCreg; ICGi008-A
Biological sample resources BioSamples; SAMEA5341576
Encyclopedic resources Wikidata; Q94313420
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number9