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Cellosaurus CUTO-3.29 (CVCL_UJ35)

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Cell line name CUTO-3.29
Synonyms CUTO3.29; Colorado University Thoracic Oncology-3.29
Accession CVCL_UJ35
Resource Identification Initiative To cite this cell line use: CUTO-3.29 (RRID:CVCL_UJ35)
Comments Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:30321; MPRIP + HGNC; HGNC:8031; NTRK1; Name(s)=MPRIP-NTRK1; Note=MPRIP exon 21 fused to NTRK1 exon 14 (PubMed=26216294).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8TE (CUTO-3)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=26216294; DOI=10.1158/2159-8290.CD-15-0443; PMCID=PMC4635026
Robert C. Doebele, Lara E. Davis, Aria Vaishnavi, Anh T. Le, Adriana Estrada-Bernal, Stephen Keysar, Antonio Jimeno, Marileila Varella-Garcia, Dara L. Aisner, Ya-Li Li, Philip J. Stephens ...Show all 16 authors... , Deborah Morosini, Brian B. Tuch, Michele Fernandes, Nisha Nanda, Jennifer A. Low; Show fewer authors
An oncogenic NTRK fusion in a patient with soft-tissue sarcoma with response to the tropomyosin-related kinase inhibitor LOXO-101.
Cancer Discov. 5:1049-1057(2015)

Cross-references
Encyclopedic resources Wikidata; Q93460571
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number9