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Cellosaurus 53Bp1-/- MEF (CVCL_UJ19)

[Text version]
Cell line name 53Bp1-/- MEF
Synonyms 53Bp1-/-
Accession CVCL_UJ19
Resource Identification Initiative To cite this cell line use: 53Bp1-/- MEF (RRID:CVCL_UJ19)
Comments Knockout cell: Method=KO mouse; MGI; MGI:1351320; Trp53bp1.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 12-13FD
Category Finite cell line
Publications

PubMed=20362325; DOI=10.1016/j.cell.2010.03.012; PMCID=PMC2857570
Bunting S.F., Callen E., Wong N., Chen H.-T., Polato F., Gunn A., Bothmer A., Feldhahn N., Fernandez-Capetillo O., Cao L., Xu X.-L., Deng C.-X., Finkel T., Nussenzweig M.C., Stark J.M., Nussenzweig A.
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Cell 141:243-254(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3257
Encyclopedic resources Wikidata; Q93307782
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number6