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Cellosaurus Brca1 delta11/delta11 53Bp1-/- MEF (S7) (CVCL_UJ18)

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Cell line name Brca1 delta11/delta11 53Bp1-/- MEF (S7)
Synonyms Brac1 delta11/delta1153Bp1-/- (S7)
Accession CVCL_UJ18
Resource Identification Initiative To cite this cell line use: Brca1 delta11/delta11 53Bp1-/- MEF (S7) (RRID:CVCL_UJ18)
Comments Characteristics: Established from mice homologous for Brca1 Ex11del.
Knockout cell: Method=KO mouse; MGI; MGI:1351320; Trp53bp1.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 12-13FD
Category Finite cell line
Publications

PubMed=20362325; DOI=10.1016/j.cell.2010.03.012; PMCID=PMC2857570
Samuel F. Bunting, Elsa Callen, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao, Xiao-Ling Xu ...Show all 16 authors... , Chu-Xia Deng, Toren Finkel, Michel Claudio Nussenzweig, Jeremy M. Stark, Andre Nussenzweig; Show fewer authors
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Cell 141:243-254(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3264
Encyclopedic resources Wikidata; Q93431460
Entry history
Entry creation25-Feb-2019
Last entry update29-Jun-2023
Version number6