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Cellosaurus hTERT SC ipn02.3 2lambda (CVCL_UI64)

[Text version]
Cell line name hTERT SC ipn02.3 2lambda
Synonyms ipn02.3 2lambda; ipn02.3, 2lambda; ipn02.3
Accession CVCL_UI64
Resource Identification Initiative To cite this cell line use: hTERT SC ipn02.3 2lambda (RRID:CVCL_UI64)
Comments Doubling time: 38.8 hours (ATCC=CRL-3392).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral nervous system, sural nerve; UBERON=UBERON_0015488.
Cell type: Schwann cell; CL=CL_0002573.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-3392; PubMed=27617404

Markers:
AmelogeninX
CSF1PO10,11
D2S133816,17
D3S135817,18
D5S8188,11
D7S8208,12
D8S117912,15
D13S31712,13
D16S53912
D18S5113,16
D19S43314
D21S1130.2,32.2
FGA23,24
Penta D11
Penta E17,18
TH016,7
TPOX8,12
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; NTAP; -; https://www.n-tap.org/for-researchers/cell-model-systems
Publications

PubMed=27617404; DOI=10.1038/labinvest.2016.88
Hua Li, Lung-Ji Chang, Debbie R. Neubauer, David F. Muir 4th, Margaret R. Wallace;
Immortalization of human normal and NF1 neurofibroma Schwann cells.
Lab. Invest. 96:1105-1115(2016)

PubMed=29055717; DOI=10.1016/j.expneurol.2017.10.012; PMCID=PMC6863155
Janice M. Kraniak, Anita Chalasani, Margaret R. Wallace, Raymond Richard Mattingly;
Development of 3D culture models of plexiform neurofibroma and initial application for phenotypic characterization and drug screening.
Exp. Neurol. 299:289-298(2018)

PubMed=29893754; DOI=10.1038/sdata.2018.106; PMCID=PMC5996849
Marc Ferrer, Sara J. Calafell Gosline, Marigo Stathis, Xiao-Hu Zhang, Xin-Di Guo, Rajarshi Guha, Dannielle A. Ryman, Margaret R. Wallace, Laura Kasch-Semenza, Hai-Ping Hao, Roxann G. Ingersoll ...Show all 16 authors... , David Mohr, Craig J. Thomas, Sharad Verma, Justin H. Guinney, Jaishri O'Neill Blakeley; Show fewer authors
Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived Schwann cells.
Sci. Data 5:180106.1-180106.12(2018)

Cross-references
Cell line collections (Providers) ABM; T0181
ATCC; CRL-3392
Encyclopedic resources Wikidata; Q94305879
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number10