Cellosaurus logo
expasy logo

Cellosaurus hTERT SC ipn02.3 2lambda (CVCL_UI64)

[Text version]
Cell line name hTERT SC ipn02.3 2lambda
Synonyms ipn02.3 2lambda; ipn02.3, 2lambda; ipn02.3
Accession CVCL_UI64
Resource Identification Initiative To cite this cell line use: hTERT SC ipn02.3 2lambda (RRID:CVCL_UI64)
Comments Doubling time: 38.8 hours (ATCC=CRL-3392).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral nervous system, sural nerve; UBERON=UBERON_0015488.
Cell type: Schwann cell; CL=CL_0002573.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-3392; PubMed=27617404

Markers:
AmelogeninX
CSF1PO10,11
D2S133816,17
D3S135817,18
D5S8188,11
D7S8208,12
D8S117912,15
D13S31712,13
D16S53912
D18S5113,16
D19S43314
D21S1130.2,32.2
FGA23,24
Penta D11
Penta E17,18
TH016,7
TPOX8,12
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; NTAP; -; https://www.n-tap.org/for-researchers/cell-model-systems
Publications

PubMed=27617404; DOI=10.1038/labinvest.2016.88
Li H., Chang L.-J., Neubauer D.R., Muir D.F. 4th, Wallace M.R.
Immortalization of human normal and NF1 neurofibroma Schwann cells.
Lab. Invest. 96:1105-1115(2016)

PubMed=29055717; DOI=10.1016/j.expneurol.2017.10.012; PMCID=PMC6863155
Kraniak J.M., Chalasani A., Wallace M.R., Mattingly R.R.
Development of 3D culture models of plexiform neurofibroma and initial application for phenotypic characterization and drug screening.
Exp. Neurol. 299:289-298(2018)

PubMed=29893754; DOI=10.1038/sdata.2018.106; PMCID=PMC5996849
Ferrer M., Gosline S.J.C., Stathis M., Zhang X.-H., Guo X.-D., Guha R., Ryman D.A., Wallace M.R., Kasch-Semenza L., Hao H.-P., Ingersoll R.G., Mohr D., Thomas C.J., Verma S., Guinney J.H., Blakeley J.O.
Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived Schwann cells.
Sci. Data 5:180106.1-180106.12(2018)

Cross-references
Cell line collections (Providers) ABM; T0181
ATCC; CRL-3392
Encyclopedic resources Wikidata; Q94305879
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number9