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Cellosaurus NPC38 (CVCL_UH63)

[Text version]
Cell line name NPC38
Accession CVCL_UH63
Resource Identification Initiative To cite this cell line use: NPC38 (RRID:CVCL_UH63)
Comments Population: Chinese.
Omics: Transcriptomics; RNAseq.
Caution: Shows histological features of squamous cell carcinoma, and no EBV infection. Hence it may represent an independent primary squamous cell carcinoma induced by radiotherapy at the recurrent site of NPC (PubMed=30405107).
Derived from site: In situ; Pharynx, nasopharynx; UBERON=UBERON_0001728.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): PubMed=30405107

Markers:
AmelogeninX
CSF1PO12,13
D2S133823,25
D3S135818,19
D5S81810,12
D7S8208,10,11,12
D8S117912,13,14
D13S3178,9,10
D16S53910
D18S5113,21
D19S43313.2,15.2
D21S1130,33.2
FGA23,25
TH016,9
TPOX8,10
vWA18

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Publications

PubMed=30405107; DOI=10.1038/s41467-018-06889-5; PMCID=PMC6220246
Lin W.-T., Yip Y.-L., Jia L., Deng W., Zheng H., Dai W., Ko J.M.-Y., Lo K.-W., Chung G.T.-Y., Yip K.Y.-L., Lee S.-D., Kwan J.S.-H., Zhang J., Liu T.-F., Chan J.Y.-W., Kwong D.L.-W., Lee V.H.-F., Nicholls J.M., Busson P., Liu X.-F., Chiang A.K.-S., Hui K.-F., Kwok H., Cheung S.-T., Cheung Y.-C., Chan C.-K., Li B., Cheung A.L.-M., Hau P.-M., Zhou Y., Tsang C.-M., Middeldorp J.M., Chen H.-L., Lung M.L., Tsao S.-W.
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.
Nat. Commun. 9:4663.1-4663.17(2018)

DOI=10.1016/B978-0-12-814936-2.00005-5
Yip Y.-L., Lin W.-T., Deng W., Tsang C.-M., Tsao S.-W.
Establishment of nasopharyngeal carcinoma cell lines, patient-derived xenografts, and immortalized nasopharyngeal epithelial cell lines for nasopharyngeal carcinoma and Epstein-Barr virus infection studies.
(In book chapter) Nasopharyngeal carcinoma. From etiology to clinical practice; Lee A.W.-M., Lung M.L., Ng W.T. (eds.); pp.85-107; Academic Press; New York; USA (2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01993
Encyclopedic resources Wikidata; Q98128016
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number9