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Cellosaurus HEK-Blue hTLR2 KO-TLR1/6 (CVCL_UF27)

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Cell line name HEK-Blue hTLR2 KO-TLR1/6
Accession CVCL_UF27
Resource Identification Initiative To cite this cell line use: HEK-Blue hTLR2 KO-TLR1/6 (RRID:CVCL_UF27)
Comments Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB and AP-1-binding sites (InvivoGen=hkb-htlr2k16).
Knockout cell: Method=Not specified; HGNC; HGNC:11847; TLR1.
Knockout cell: Method=Not specified; HGNC; HGNC:16711; TLR6.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1628; CD14.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11848; TLR2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IM80 (HEK-Blue hTLR2)
Children:
CVCL_UF28 (HEK-Blue hTLR2-TLR1)CVCL_UF29 (HEK-Blue hTLR2-TLR6)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cross-references
Cell line collections (Providers) InvivoGen; hkb-htlr2k16
Encyclopedic resources Wikidata; Q94092202
Entry history
Entry creation13-Nov-2018
Last entry update10-Apr-2025
Version number9