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Cellosaurus KC13-2 (CVCL_UF16)

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Cell line name KC13-2
Synonyms Kupffer Cells 13-2
Accession CVCL_UF16
Resource Identification Initiative To cite this cell line use: KC13-2 (RRID:CVCL_UF16)
Comments Characteristics: Useful for the study of drug delivery, of phagocytosis of pathogens and apoptotic cells and of the role of Kupffer cells in transplantation (PubMed=19835055).
Characteristics: Grows stably at 33 Celsius without gamma-interferon. Also grows, more slowly, at 37 Celsius (PubMed=12832442).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Kupffer cell; CL=CL_0000091.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
Category Transformed cell line
Web pages Info; -; -; https://www.forschung3r.ch/en/publications/bu26.html
Publications

PubMed=12832442; DOI=10.1189/jlb.0302133
Daniel Dory, Hakim Echchannaoui, Maryse Letiembre, Fabrizia Ferracin, Jean Pieters, Yoshiyuki Adachi, Sachiko Akashi, Werner Zimmerli, Regine Landmann-Suter;
Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb-tsA58 mice.
J. Leukoc. Biol. 74:49-59(2003)

PubMed=19835055
Regine Landmann-Suter;
Generation and use of a mouse Kupffer cell line.
ALTEX 24 Suppl. 1:42-45(2007)

Cross-references
Encyclopedic resources Wikidata; Q94337197
Entry history
Entry creation13-Nov-2018
Last entry update14-Aug-2025
Version number10