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Cellosaurus IB-4 (CVCL_UE01)

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Cell line name IB-4
Synonyms IB4
Accession CVCL_UE01
Resource Identification Initiative To cite this cell line use: IB-4 (RRID:CVCL_UE01)
Comments Virology: Contains 4 to 5 copies of the EBV genome. These are chromosomally integrated and do not exist in an episomal form (PubMed=1645805; PubMed=15681063).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=6253674; DOI=10.1128/JVI.36.2.506-518.1980; PMCID=PMC353668
Walter King, Ann L. Thomas-Powell, Nancy Raab-Traub, Mary Hawke, Elliott Dan Kieff;
Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell line.
J. Virol. 36:506-518(1980)

PubMed=6112750; DOI=10.1073/pnas.78.3.1930; PMCID=PMC319249
Vicky L. van Santen, Andrew Cheung, Elliott Dan Kieff;
Epstein-Barr virus RNA VII: size and direction of transcription of virus-specified cytoplasmic RNAs in a transformed cell line.
Proc. Natl. Acad. Sci. U.S.A. 78:1930-1934(1981)

PubMed=1645805; DOI=10.1128/JVI.65.7.3958-3963.1991; PMCID=PMC241437
Elizabeth A. Hurley, Lori D. Klaman, Susan Agger, Jeanne Bentley Lawrence, David A. Thorley-Lawson;
The prototypical Epstein-Barr virus-transformed lymphoblastoid cell line IB4 is an unusual variant containing integrated but no episomal viral DNA.
J. Virol. 65:3958-3963(1991)

PubMed=15681063; DOI=10.1016/j.virusres.2004.08.021
Tetsuya Takakuwa, Wen-Juan Luo, Maria Francisca Ham, Naoki Wada, Katsuyuki Aozasa;
Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4).
Virus Res. 108:133-138(2005)

Cross-references
Encyclopedic resources Wikidata; Q94312417
Entry history
Entry creation13-Nov-2018
Last entry update29-Jun-2023
Version number6