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Cellosaurus LM-MEL-73 (CVCL_UC65)

[Text version]
Cell line name LM-MEL-73
Synonyms LM-Mel-73; Ludwig Melbourne-MELanoma-73
Accession CVCL_UC65
Resource Identification Initiative To cite this cell line use: LM-MEL-73 (RRID:CVCL_UC65)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Miscellaneous: PTK2B mutation, metastatic site and STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
  • Mutation; HGNC; HGNC:9612; PTK2B; Simple; p.Arg429Cys (c.1285C>T); dbSNP=rs201274282; Zygosity=Heterozygous (Direct_author_submission).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,03:01
HLA-BB*27:05,44:02
HLA-CC*02:02,05:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO10,13
D5S81812,14
D7S82010,11
D13S31712,14
D16S53910,11
D21S1129,30,31
TH017
TPOX9
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=23527996; DOI=10.1111/pcmr.12097
Andreas Behren, Matthew Anaka, Pu-Han Lo, Laura J. Vella, Ian D. Davis, Jenny Catimel, Tracy Cardwell, Craig Gedye, Christopher Hudson, Rodica Stan, Jonathan S. Cebon;
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Miles C. Andrews, Joseph Cursons, Daniel Glyn Hurley, Matthew Anaka, Jonathan S. Cebon, Andreas Behren, Edmund John Crampin;
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UC65
Encyclopedic resources Wikidata; Q95982566
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371790
Entry history
Entry creation13-Nov-2018
Last entry update10-Apr-2025
Version number13