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Cellosaurus LM-MEL-62 (CVCL_UC60)

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Cell line name LM-MEL-62
Synonyms LM-Mel-62; Ludwig Melbourne-MELanoma-62
Accession CVCL_UC60
Resource Identification Initiative To cite this cell line use: LM-MEL-62 (RRID:CVCL_UC60)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: ~38 hours (ATCC=CRL-3339).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Miscellaneous: STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly469Glu (c.1406G>A) (p.Gly509Glu, c.1526G>A); ClinVar=VCV000013974; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,31:01
HLA-BB*07:02,60
HLA-CC*03:04,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3339; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10
D5S81810,12
D7S82011
D13S31710,13
D16S53910
D21S1129,30
TH017
TPOX11
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=19221743; DOI=10.1007/s00262-009-0672-0; PMCID=PMC11029848
Craig Gedye, Juliet Quirk, Judy Browning, Suzanne Svobodova, Thomas John, Pavel Sluka, Peter Roderick Dunbar, Denis Corbeil, Jonathan S. Cebon, Ian D. Davis;
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.
Cancer Immunol. Immunother. 58:1635-1646(2009)

PubMed=22102544; DOI=10.1002/stem.786
Matthew Anaka, Claudia Freyer, Craig Gedye, Otavia L. Caballero, Ian D. Davis, Andreas Behren, Jonathan S. Cebon;
Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile.
Stem Cells 30:336-343(2012)

PubMed=23527996; DOI=10.1111/pcmr.12097
Andreas Behren, Matthew Anaka, Pu-Han Lo, Laura J. Vella, Ian D. Davis, Jenny Catimel, Tracy Cardwell, Craig Gedye, Christopher Hudson, Rodica Stan, Jonathan S. Cebon;
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Miles C. Andrews, Joseph Cursons, Daniel Glyn Hurley, Matthew Anaka, Jonathan S. Cebon, Andreas Behren, Edmund John Crampin;
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3339
Cell line databases/resources cancercelllines; CVCL_UC60
Encyclopedic resources Wikidata; Q95982557
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371785
Entry history
Entry creation13-Nov-2018
Last entry update10-Apr-2025
Version number11