Cellosaurus cell line UCSD-SAD5.17 (CVCL

Cellosaurus UCSD-SAD5.17 (CVCL_UB93)

Cross-references
Cell line name	UCSD-SAD5.17
Synonyms	UCSD-ADRC#3158
Accession	CVCL_UB93
Resource Identification Initiative	To cite this cell line use: UCSD-SAD5.17 (RRID:CVCL_UB93)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Disease	Alzheimer's disease (NCIt: C2866)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	84Y
Category	Induced pluripotent stem cell
Publications	PubMed=25772071; DOI=10.1016/j.stem.2015.02.004; PMCID=PMC4388804 Jessica E. Young, Jonathan Boulanger-Weill, Daniel A. Williams, Grace Woodruff, Floyd Buen, Arra C. Revilla, Cheryl M. Herrera, Mason A. Israel, Shauna H. Yuan, Steven D. Edland, Lawrence Steven B. Goldstein; Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells. Cell Stem Cell 16:373-385(2015) PubMed=30686764; DOI=10.1016/j.stem.2018.12.013; PMCID=PMC6414424 Rik van der Kant, Vanessa F. Langness, Cheryl M. Herrera, Daniel A. Williams, Lauren K. Fong, Yves Leestemaker, Evelyne Steenvoorden, Kevin D. Rynearson, Jos F. Brouwers, J. Bernd Helms, Huib Ovaa ...Show all 15 authors... , Martin Giera, Steven L. Wagner, Anne G. Bang, Lawrence Steven B. Goldstein; Show fewer authors Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons. Cell Stem Cell 24:363-375.e9(2019)
Encyclopedic resources	Wikidata; Q98133858
Entry history
Entry creation	13-Nov-2018
Last entry update	29-Jun-2023
Version number	6