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Cellosaurus AI11e-OTX2YFP (CVCL_UB76)

[Text version]
Cell line name AI11e-OTX2YFP
Synonyms AI11e-OTX2-YFP; OTX2 Cit/+
Accession CVCL_UB76
Resource Identification Initiative To cite this cell line use: AI11e-OTX2YFP (RRID:CVCL_UB76)
Comments Registration: Swiss research registry; BAG-hES-IMP-0109.
Characteristics: Using TALEN a FLAG-citrine-P2A-PuroR construct was introduced at the C-terminal end of one allele of OTX2.
Genetic integration: Method=TALEN; Gene=FPbase; VR7EN; Citrine (Note=Yellow fluorescent protein derived from GFP).
Genetic integration: Method=TALEN; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=28094016; DOI=10.1016/j.stem.2016.09.011; PMCID=PMC5261831
Zi-Zhen Yao, John K. Mich, Sherman Ku, Vilas Menon, Anne-Rachel F. Krostag, Refugio A. Martinez, Leon Furchtgott, Heather Mulholland, Susan Bort, Margaret A. Fuqua, Benjamin W. Gregor ...Show all 32 authors... , Rebecca D. Hodge, Anu Jayabalu, Ryan C. May, Samuel Melton, Angelique M. Nelson, N. Kiet Ngo, Nadiya V. Shapovalova, Soraya I. Shehata, Michael W. Smith, Leah J. Tait, Carol L. Thompson, Elliot R. Thomsen, Chao-Yang Ye, Ian A. Glass, Ajamete Kaykas, Shu-Yuan Yao, John W. Phillips, Joshua S. Grimley, Boaz P. Levi, Yan-Ling Wang, Sharad Ramanathan; Show fewer authors
A single-cell roadmap of lineage bifurcation in human ESC models of embryonic brain development.
Cell Stem Cell 20:120-134(2017)

Cross-references
Cell line collections (Providers) WiCell; ai11e-otx2yfp
Encyclopedic resources Wikidata; Q93323864
Entry history
Entry creation13-Nov-2018
Last entry update14-Aug-2025
Version number8