Cellosaurus cell line SK-MEL-27-2 (CVCL

Cross-references
Cell line name	SK-MEL-27-2
Synonyms	SKMEL-27-2
Accession	CVCL_U914
Resource Identification Initiative	To cite this cell line use: SK-MEL-27-2 (RRID:CVCL_U914)
Comments	From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=21725359).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_6030 (SK-MEL-27)
Sex of cell	Female
Age at sampling	52Y
Category	Cancer cell line
Publications	PubMed=21725359; DOI=10.1038/onc.2011.250; PMCID=PMC3267014 Feng Xing, Yogindra Persaud, Christine A. Pratilas, Barry Stephen Taylor, Manickam Janakiraman, Qing-Bai She, Humilidad F. Gallardo, C. Liu, Taha Merghoub, Blake E. Hefter, Igor Dolgalev ...Show all 19 authors... , Agnes J. Viale, Adriana Heguy, Elisa de Stanchina, David Cobrinik, Gideon Bollag, Jedd D. Wolchok, Alan N. Houghton, David B. Solit; Show fewer authors Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF. Oncogene 31:446-457(2012)
Cell line databases/resources	cancercelllines; CVCL_U914
Encyclopedic resources	Wikidata; Q54954002
Polymorphism and mutation databases	Cosmic; 1669143
Entry history
Entry creation	16-Apr-2014
Last entry update	19-Dec-2024
Version number	12