Cellosaurus logo
expasy logo

Cellosaurus EBC-1/bone (CVCL_U892)

[Text][XML][JSON]
Cell line name EBC-1/bone
Accession CVCL_U892
Resource Identification Initiative To cite this cell line use: EBC-1/bone (RRID:CVCL_U892)
Comments Population: Chinese; Taiwan.
Characteristics: Bone metastatic. Established from parent cell line in athymic mice after 5 cycles of in vivo serial passage of the cells in the mouse bone metastatic lesions.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:2731; DDR2; Simple; p.Thr681Ile (c.2042C>T); ClinVar=VCV001435412; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2891 (EBC-1)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=14965364; DOI=10.1111/j.1349-7006.2004.tb03195.x; PMCID=PMC11158200
Tatsuya Yoshimasu, Teruhisa Sakurai, Shoji Oura, Issei Hirai, Hirokazu Tanino, Yozo Kokawa, Yasuaki Naito, Yoshitaka Okamura, Ichiro Ota, Naoyuki Tani, Nariaki Matsuura;
Increased expression of integrin alpha3beta1 in highly brain metastatic subclone of a human non-small cell lung cancer cell line.
Cancer Sci. 95:142-148(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U892
Encyclopedic resources Wikidata; Q54831758
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number17