Cellosaurus cell line KD [Human abdomen rhabdoid tumor] (CVCL

Cellosaurus KD [Human abdomen rhabdoid tumor] (CVCL_U757)

Cross-references
Cell line name	KD [Human abdomen rhabdoid tumor]
Accession	CVCL_U757
Resource Identification Initiative	To cite this cell line use: KD [Human abdomen rhabdoid tumor] (RRID:CVCL_U757)
Comments	Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Omics: Genomics; Whole exome sequencing. Derived from site: In situ; Abdomen; UBERON=UBERON_0000916.
Sequence variations	Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Heterozygous (PubMed=9671307).
Disease	Extrarenal rhabdoid tumor (NCIt: C6586) Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	11M
Category	Cancer cell line
Publications	PubMed=9671307; DOI=10.1038/28212 Isabella Versteege, Nicolas Sevenet, Julian Lange, Marie-Francoise Rousseau-Merck, Peter F. Ambros, Rupert Handgretinger, Alain Aurias, Olivier Delattre; Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203-206(1998) PubMed=10397258 Marie-Francoise Rousseau-Merck, Isabella Versteege, Isabelle Legrand, Jerome Couturier, Aline Mairal, Olivier Delattre, Alain Aurias; hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors. Cancer Res. 59:3152-3156(1999) PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569:503-508(2019)
Cell line databases/resources	cancercelllines; CVCL_U757 Cell_Model_Passport; SIDM01663 DepMap; ACH-001099
Biological sample resources	BioSample; SAMN10989606
Encyclopedic resources	Wikidata; Q54899702
Polymorphism and mutation databases	Cosmic; 802251
Entry history
Entry creation	16-Apr-2014
Last entry update	10-Apr-2025
Version number	14