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Cellosaurus AE1-2a (CVCL_U656)

[Text version]
Cell line name AE1-2a
Synonyms AE1-2A
Accession CVCL_U656
Resource Identification Initiative To cite this cell line use: AE1-2a (RRID:CVCL_U656)
Comments Population: Caucasian.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_U662 (601)CVCL_E066 (633)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=8648763; DOI=10.1128/JVI.70.6.4173-4178.1996
Gorziglia M.I., Kadan M.J., Yei S., Lim J., Lee G.M., Luthra R., Trapnell B.C.
Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy.
J. Virol. 70:4173-4178(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U656
Encyclopedic resources Wikidata; Q54608893
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number11