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Cellosaurus AE1-2a (CVCL_U656)

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Cell line name AE1-2a
Synonyms AE1-2A
Accession CVCL_U656
Resource Identification Initiative To cite this cell line use: AE1-2a (RRID:CVCL_U656)
Comments Population: Caucasian.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_U662 (601)CVCL_E066 (633)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=8648763; DOI=10.1128/JVI.70.6.4173-4178.1996; PMCID=PMC190312
Mario I. Gorziglia, Michael J. Kadan, Soonpin Yei, Jin Lim, Gai M. Lee, Rajni Luthra, Bruce C. Trapnell;
Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy.
J. Virol. 70:4173-4178(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U656
Encyclopedic resources Wikidata; Q54608893
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number12