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Cellosaurus MSC-1 (CVCL_U446)

[Text version]
Cell line name MSC-1
Synonyms Mouse Sertoli Cell line-1
Accession CVCL_U446
Resource Identification Initiative To cite this cell line use: MSC-1 (RRID:CVCL_U446)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=ts1609).
Derived from site: In situ; Testis; UBERON=UBERON_0000473.
Cell type: Sertoli cell; CL=CL_0000216.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: hMIS-SV40 transgenic.
Hierarchy Children:
CVCL_U447 (MSCFSHR-1)
Sex of cell Male
Age at sampling 13W
Category Transformed cell line
Publications

PubMed=1331774; DOI=10.1210/mend.6.9.1331774
Jacques J. Peschon, Richard R. Behringer, Richard L. Cate, Kimberly A. Harwood, Rejean L. Idzerda, Ralph Lawrence Brinster, Richard DeForest Palmiter;
Directed expression of an oncogene to Sertoli cells in transgenic mice using Mullerian inhibiting substance regulatory sequences.
Mol. Endocrinol. 6:1403-1411(1992)

PubMed=7918865; DOI=10.1095/biolreprod51.1.116
Michael P. McGuinness, Carol C. Linder, Carlos R. Morales, Leslie L. Heckert, Jeremie Pikus, Michael D. Griswold;
Relationship of a mouse Sertoli cell line (MSC-1) to normal Sertoli cells.
Biol. Reprod. 51:116-124(1994)

PubMed=15541572; DOI=10.1016/j.mce.2003.05.001
Nafis A. Rahman, Ilpo Tapani Huhtaniemi;
Testicular cell lines.
Mol. Cell. Endocrinol. 228:53-65(2004)

PubMed=22553484; DOI=10.4161/spmg.19885; PMCID=PMC3341241
Gurvinder Kaur, Jannette M. Dufour;
Cell lines: valuable tools or useless artifacts.
Spermatogenesis 2:1-5(2012)

Cross-references
Encyclopedic resources Wikidata; Q54906821
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number12