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Cellosaurus 9HTEo- (CVCL_U405)

[Text version]
Cell line name 9HTEo-
Synonyms 9/HTEo-; 9/HTEo(-); 9/HTEo; HTE-9o-; 9HTE
Accession CVCL_U405
Resource Identification Initiative To cite this cell line use: 9HTEo- (RRID:CVCL_U405)
Comments Characteristics: Useful model for the study of epithelial ion transport, secretion and biochemistry and frequently used as a wild-type control for cystic fibrosis tracheobronchial epithelial cells (Millipore=SCC153).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Trachea; UBERON=UBERON_0003126.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_HJ44 (9HTEo-/Dx)CVCL_HJ45 (9HTEo-/S)
Originate from same individual CVCL_U403 ! 3HTEo-
CVCL_U404 ! 8HTEo-
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): Millipore=SCC153

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,17
D5S81810,12
D7S8208,12
D8S117915
D13S3179
D16S53911
D18S5114
D21S1130,32.2
FGA25,26
Penta D13
Penta E10,11
TH018
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages Info; Dartmouth; -; https://web.archive.org/web/20190126194809/http://www.dartmouth.edu/~cysfib/cell-lines.html
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/9/cell-lines-detail-469.html
Publications

PubMed=2457904; DOI=10.1073/pnas.85.16.5951; PMCID=PMC281883
Gruenert D.C., Basbaum C.B., Welsh M.J., Li M., Finkbeiner W.E., Nadel J.A.
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40.
Proc. Natl. Acad. Sci. U.S.A. 85:5951-5955(1988)

PubMed=1282304; DOI=10.1152/ajplung.1992.263.6.L692
Haws C., Krouse M.E., Xia Y.-F., Gruenert D.C., Wine J.J.
CFTR channels in immortalized human airway cells.
Am. J. Physiol. 263:L692-L707(1992)

PubMed=1375758; DOI=10.1073/pnas.89.11.5171; PMCID=PMC49251
Cozens A.L., Yezzi M.J., Chin L., Simon E.M., Finkbeiner W.E., Wagner J.A., Gruenert D.C.
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 89:5171-5175(1992)

PubMed=8843701; DOI=10.1152/ajpcell.1996.271.3.C728
Galietta L.J.V., Romeo G., Zegarra-Moran O.
Volume regulatory taurine release in human tracheal 9HTEo- and multidrug resistant 9HTEo-/Dx cells.
Am. J. Physiol. 271:C728-C735(1996)

PubMed=10498856; DOI=10.1038/sj.bjp.0702772; PMCID=PMC1571611
Goncz K.K., Feeney L., Gruenert D.C.
Differential sensitivity of normal and cystic fibrosis airway epithelial cells to epinephrine.
Br. J. Pharmacol. 128:227-233(1999)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Cell line collections (Providers) Millipore; SCC153
Encyclopedic resources Wikidata; Q54605931
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number16