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Cellosaurus AG04110 (CVCL_U311)

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Cell line name AG04110
Accession CVCL_U311
Resource Identification Initiative To cite this cell line use: AG04110 (RRID:CVCL_U311)
Comments Population: Caucasian.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Caution: Is stated not be from a Werner syndrome patient by PubMed=26984941.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:6636; LMNA; Simple; p.Glu578Val (c.1733A>T); ClinVar=VCV000066863; Zygosity=Heterozygous (Coriell=AG04110).
Disease Werner syndrome (NCIt: C3447)
Atypical Werner syndrome (ORDO: Orphanet_79474)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WU12 (AG27427)
Sex of cell Female
Age at sampling 13Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=26984941; DOI=10.1093/hmg/ddw079; PMCID=PMC5062591
Wei-Liang Tang, Ana I. Robles, Richard P. Beyer, Lucas T. Graybuck, Giang Huong Nguyen, Junko Oshima, Nancy Maizels, Curtis Craig Harris, Raymond J. Monnat Jr.;
The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.
Hum. Mol. Genet. 25:2060-2069(2016)

Cross-references
Cell line collections (Providers) Coriell; AG04110
Cell line databases/resources CLO; CLO_0034776
Encyclopedic resources Wikidata; Q54609925
Gene expression databases GEO; GSM1535463
GEO; GSM1535468
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number17