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Cellosaurus RH9/CB (CVCL_U265)

[Text version]
Cell line name RH9/CB
Accession CVCL_U265
Resource Identification Initiative To cite this cell line use: RH9/CB (RRID:CVCL_U265)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11622.
Population: Caucasian.
Characteristics: Established from parent cell line by co-cultivation with peripheral blood mononuclear cells isolated from a patient with idiopathic CD4 + T lymphocitopenia (ICL). Contains human intracisternal A-type particles type II (HIAP-II) (IZSLER=BS TCL 164).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Sezary syndrome (NCIt: C3366)
Sezary syndrome (ORDO: Orphanet_3162)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U264 (RH9)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

Patent=US5580772
Robert F. Garry Jr.;
Association between a novel human intracisternal A-type retroviral particle-type II (HIAP-II) and idiopathic CD4+ T-lymphocytopenia (ICL).
Patent number US5580772, 03-Dec-1996

Cross-references
Cell line collections (Providers) IZSLER; BS TCL 164
Cell line databases/resources cancercelllines; CVCL_U265
Encyclopedic resources Wikidata; Q54950373
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number16