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Cellosaurus MCAS-3 (CVCL_U210)

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Cell line name MCAS-3
Accession CVCL_U210
Resource Identification Initiative To cite this cell line use: MCAS-3 (RRID:CVCL_U210)
Comments Population: Japanese.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Ser504Arg (c.1512T>A); Zygosity=Unspecified (from parent cell line).
Disease Ovarian mucinous cystadenocarcinoma (NCIt: C4026)
Mucinous adenocarcinoma of ovary (ORDO: Orphanet_398961)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3020 (MCAS)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=7882618; DOI=10.1007/BF00133613
Etsuko Miyagi, Hidetaro Yasumitsu, Fumiki Hirahara, Yoji Nagashima, Hiroshi Minaguchi, Kaoru Miyazaki, Makoto Umeda;
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Clin. Exp. Metastasis 13:89-96(1995)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U210
Encyclopedic resources Wikidata; Q54904242
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number14