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Cellosaurus MR1-3 (CVCL_U180)

[Text version]

Cell line name MR1-3
Accession CVCL_U180
Resource Identification Initiative To cite this cell line use: MR1-3 (RRID:CVCL_U180)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from sampling site: Uterus; cervix.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U209 (HeLa S3 mer-)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=25877200; RCB

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D7S8208
D8S117912
D13S31713.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,15
Penta E7,16,17
TH017
TPOX8,12
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=3608093; DOI=10.1093/carcin/8.8.1109
Ishida R., Takahashi T.
N-methyl-N'-nitro-N-nitrosoguanidine-resistant HeLa S3 cells still have little O6-methylguanine-DNA methyltransferase activity and are hypermutable by alkylating agents.
Carcinogenesis 8:1109-1113(1987)

PubMed=2372878; DOI=10.1093/carcin/11.7.1209
Ishida R., Utsumi K.R.
Differences in induction of sister chromatid exchanges in MNNG-resistant HeLa S3 Mer- cell lines.
Carcinogenesis 11:1209-1212(1990)

Cross-references
Cell line collections RCB; RCB0504
Cell line databases/resources CLO; CLO_0050915
Biological sample resources BioSample; SAMN03470994
Encyclopedic resources Wikidata; Q54906568
Polymorphism and mutation databases Cosmic; 753593
Entry history
Entry creation03-Feb-2014
Last entry update29-Oct-2020
Version number12