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Cellosaurus Rov9 (CVCL_U156)

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Cell line name Rov9
Accession CVCL_U156
Resource Identification Initiative To cite this cell line use: Rov9 (RRID:CVCL_U156)
Comments Characteristics: After exposure to scrapie agent, cultures were repeatedly found to accumulate high levels of abnormal PrP (PrPres) (PubMed=11259656).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P23907; Sheep PRNP (Note=With p.Ala136Val and p.Arg171Gln = VRQ allele).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Oryctolagus cuniculus (Rabbit) (NCBI Taxonomy: 9986)
Hierarchy Parent: CVCL_3155 (RK 13)
Sex of cell Sex unspecified
Age at sampling 5W
Category Spontaneously immortalized cell line
Publications

PubMed=11259656; DOI=10.1073/pnas.061337998; PMCID=PMC31178
Didier Vilette, Olivier Andreoletti, Fabienne Archer, Marie-Francoise Madelaine, Jean-Luc Vilotte, Sylvain Lehmann, Hubert Laude;
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein.
Proc. Natl. Acad. Sci. U.S.A. 98:4055-4059(2001)

Cross-references
Encyclopedic resources Wikidata; Q54950842
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number14