• Gene fusion; HGNC; 9113; PML + HGNC; 9864; RARA; Name(s)=PML-RARA (PubMed=12353268).
  
• Mutation; HGNC; 6407; KRAS; Simple; p.Ala18Asp (c.53C>A); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
  

PubMed=7719237; DOI=10.3109/10428199509049768
Dermime S., Grignani F., Rogaia D., Liberatore C., Marchesi E., Gambacorti-Passerini C.
Acute promyelocytic leukaemia cells resistant to retinoic acid show further perturbation of the RAR alpha signal transduction system.
Leuk. Lymphoma 16:289-295(1995)

PubMed=11704857; DOI=10.1038/sj.onc.1204863
Roussel M.J.S., Lanotte M.
Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes.
Oncogene 20:7287-7291(2001)

PubMed=12353268; DOI=10.1002/gcc.10117
Mozziconacci M.-J., Rosenauer A., Restouin A., Fanelli M., Shao W.-L., Fernandez F., Toiron Y., Viscardi J., Gambacorti-Passerini C., Miller W.H. Jr., Lafage-Pochitaloff M.
Molecular cytogenetics of the acute promyelocytic leukemia-derived cell line NB4 and of four all-trans retinoic acid-resistant subclones.
Genes Chromosomes Cancer 35:261-270(2002)