Cellosaurus logo
expasy logo

Cellosaurus HAP1 VPS35 (-) 5 (CVCL_TX57)

[Text version]
Cell line name HAP1 VPS35 (-) 5
Synonyms HZGHC000863c012; VPS35 knockout cell line 11bp deletion
Accession CVCL_TX57
Resource Identification Initiative To cite this cell line use: HAP1 VPS35 (-) 5 (RRID:CVCL_TX57)
Comments Group: Haploid karyotype cell line.
Knockout cell: Method=CRISPR/Cas9; HGNC; 13487; VPS35.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y019 (HAP1)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

DOI=10.12688/f1000research.133696.1
Ayoubi R., Fotouhi M., Southern K., McPherson P.S., Laflamme C.
The identification of high-performing antibodies for vacuolar protein sorting-associated protein 35 (hVPS35) for use in western blot, immunoprecipitation and immunofluorescence.
F1000Research 12:452.1-452.13(2023)

Cross-references
Cell line collections (Providers) Horizon_Discovery; HZGHC000863c012
Cell line databases/resources cancercelllines; CVCL_TX57
Encyclopedic resources Wikidata; Q54881077
Entry history
Entry creation14-May-2018
Last entry update05-Oct-2023
Version number9