Cellosaurus cell line JG2/1 (CVCL

Cellosaurus JG2/1 (CVCL_T960)

Cross-references
Cell line name	JG2/1
Synonyms	JG2.1; IO/JG2/1
Accession	CVCL_T960
Resource Identification Initiative	To cite this cell line use: JG2/1 (RRID:CVCL_T960)
Comments	Group: Patented cell line. Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-1695. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58). Derived from site: In situ; Eye, retina; UBERON=UBERON_0000966. Cell type: Retinal endothelial cell; CL=CL_0002585.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Lewis; RS=RS_0000121.
Sex of cell	Female
Category	Transformed cell line
Publications	DOI=10.1007/978-1-4757-9489-2_46 Peter Adamson, Gareth Pryce, Virginia L. Calder, John Greenwood; Development and characterization of SV40 large T immortalized endothelial cells of the rat blood-brain and blood-retinal barriers. (In book chapter) Biology and physiology of the blood-brain barrier. Advances in behavioral biology, Vol. 46; Couraud, Pierre-Olivier & Scherman, Daniel (eds.); pp.285-292; Springer; Boston; USA (1996) PubMed=8982103; DOI=10.1016/S0165-5728(96)00130-0 John Greenwood, Gareth Pryce, Lesley Devine, David K. Male, Washington Luis Conrado dos Santos, Virginia L. Calder, Peter Adamson; SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics. J. Neuroimmunol. 71:51-63(1996) PubMed=10734001; DOI=10.1093/brain/123.4.698 Kirsty A. Harkness, Peter Adamson, Jon David Sussman, Gwilym Aelwyn Benjamin Davies-Jones, John Greenwood, Margot Nicola Woodroofe; Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium. Brain 123:698-709(2000) Patent=US6878544 John Greenwood, Peter Adamson, Raymond Douglas Lund, Weng Tao; Retinal cell lines with extended life-span and their applications. Patent number US6878544, 12-Apr-2005
Encyclopedic resources	Wikidata; Q54898620
Entry history
Entry creation	03-Feb-2014
Last entry update	10-Apr-2025
Version number	15