Cellosaurus cell line PB1 (CVCL

Cellosaurus PB1 (CVCL_T881)

Cross-references
Cell line name	PB1
Accession	CVCL_T881
Resource Identification Initiative	To cite this cell line use: PB1 (RRID:CVCL_T881)
Comments	Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:8607; PRKN; Unexplicit; Ex6-7del; Zygosity=Homozygous (PubMed=23039195).
Disease	Parkinson disease 2, autosomal recessive juvenile (NCIt: C198603) Young-onset Parkinson disease (ORDO: Orphanet_2828)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_ZX89 (PB(DF))
Sex of cell	Male
Age at sampling	50Y
Category	Induced pluripotent stem cell
Publications	PubMed=23039195; DOI=10.1186/1756-6606-5-35; PMCID=PMC3546866 Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Masato Koike, Naoko Kuzumaki, Hideki Hayakawa, Tomoko Nihira, Tetsuro Kobayashi, Manabu Ohyama, Shigeto Sato, Masashi Takanashi ...Show all 30 authors... , Manabu Funayama, Akiyoshi Hirayama, Tomoyoshi Soga, Takako Hishiki, Makoto Suematsu, Takuya Yagi, Daisuke Ito, Arifumi Kosakai, Kozo Hayashi, Masanobu Shouji, Atsushi Nakanishi, Norihiro Suzuki, Yoshikuni Mizuno, Noboru Mizushima, Masayuki Amagai, Yasuo Uchiyama, Hideki Mochizuki, Nobutaka Hattori, Hideyuki Okano; Show fewer authors Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol. Brain 5:35.1-35.13(2012)
Cell line databases/resources	SKIP; SKIP000202
Encyclopedic resources	Wikidata; Q54938341
Entry history
Entry creation	03-Feb-2014
Last entry update	19-Dec-2024
Version number	12