Cellosaurus cell line ND35367 (CVCL

Cellosaurus ND35367 (CVCL_T845)

Cross-references
Cell line name	ND35367
Synonyms	ND35367C; ND35367F
Accession	CVCL_T845
Resource Identification Initiative	To cite this cell line use: ND35367 (RRID:CVCL_T845)
Comments	Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Homozygous (NHCDR=ND35367).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A9R0 (ND32948)
Sex of cell	Male
Age at sampling	79Y
Category	Induced pluripotent stem cell
Publications	PubMed=26651604; DOI=10.1016/j.stemcr.2015.11.004; PMCID=PMC4682343 Andrew J. Schwab, Allison D. Ebert; Neurite aggregation and calcium dysfunction in iPSC-derived sensory neurons with Parkinson's disease-related LRRK2 G2019S mutation. Stem Cell Reports 5:1039-1052(2015) PubMed=27264186; DOI=10.1016/j.celrep.2016.05.022 Lin Lin, Jonathan Goke, Engin Cukuroglu, Mark R. Dranias, Antonius M.J. VanDongen, Lawrence Walter Stanton; Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse Parkinson's disease patients. Cell Rep. 15:2411-2426(2016)
Cell line collections (Providers)	Coriell; ND35367 - Discontinued NHCDR; ND35367
Cell line databases/resources	SKIP; SKIP001369 SKIP; SKIP004684
Biological sample resources	BioSample; SAMN00805709
Encyclopedic resources	Wikidata; Q54929852
Entry history
Entry creation	03-Feb-2014
Last entry update	19-Dec-2024
Version number	21