Cellosaurus cell line P59M8 (CVCL

Cellosaurus P59M8 (CVCL_T837)

Cross-references
Cell line name	P59M8
Synonyms	59M8; P59-M08; HPS0061
Accession	CVCL_T837
Resource Identification Initiative	To cite this cell line use: P59M8 (RRID:CVCL_T837)
Comments	Omics: Transcriptomics; Microarray. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:10012; RHO; Simple; p.Gly188Arg (c.562G>A); ClinVar=VCV000143081; Zygosity=Unspecified (PubMed=21347327).
Disease	Retinitis pigmentosa (NCIt: C85045) Retinitis pigmentosa (ORDO: Orphanet_791)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_QX16 ! 59SCV3 CVCL_QX17 ! 59SV3 CVCL_QX18 ! 59SV4 CVCL_QX19 ! 59SV9 CVCL_QX67 ! P59M9
Sex of cell	Male
Age at sampling	40Y
Category	Induced pluripotent stem cell
Publications	PubMed=21347327; DOI=10.1371/journal.pone.0017084; PMCID=PMC3037398 Zi-Bing Jin, Satoshi Okamoto, Fumitaka Osakada, Kohei Homma, Juthaporn Assawachananont, Yasuhiko Hirami, Takeshi Iwata, Masayo Takahashi; Modeling retinal degeneration using patient-specific induced pluripotent stem cells. PLoS ONE 6:e17084.1-e17084.8(2011) PubMed=24527394; DOI=10.1016/j.stemcr.2013.12.007; PMCID=PMC3923225 Hiroyuki Kamao, Michiko Mandai, Satoshi Okamoto, Noriko Sakai, Akiko Suga, Sunao Sugita, Junichi Kiryu, Masayo Takahashi; Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application. Stem Cell Reports 2:205-218(2014) Patent=US10519422 Masayo Takahashi, Satoshi Okamoto, Noriko Sakai; Method of producing human retinal pigment epithelial cells. Patent number US10519422, 31-Dec-2019
Cell line collections (Providers)	RCB; HPS0061
Cell line databases/resources	SKIP; SKIP000143
Encyclopedic resources	Wikidata; Q54937310
Gene expression databases	GEO; GSM1227442
Entry history
Entry creation	03-Feb-2014
Last entry update	10-Apr-2025
Version number	17