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Cellosaurus imHCE_GDLD (CVCL_T054)

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Cell line name imHCE_GDLD
Synonyms immortalized Human Conjunctival Epithelial cells from Gelatinous Drop-Like Corneal Dystrophy patient
Accession CVCL_T054
Resource Identification Initiative To cite this cell line use: imHCE_GDLD (RRID:CVCL_T054)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Eye, conjunctival epithelium; UBERON=UBERON_0006763.
Cell type: Epithelial cell of conjunctiva; CL=CL_1000432.
Sequence variations
Disease Gelatinous drop-like corneal dystrophy (NCIt: C142805)
Gelatinous drop-like corneal dystrophy (ORDO: Orphanet_98957)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 59Y
Category Transformed cell line
Publications

PubMed=23818740; PMCID=PMC3671362
Shigeru Kinoshita, Satoshi Kawasaki, Koji Kitazawa, Katsuhiko Shinomiya;
Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 110:166-177(2012)

PubMed=23868985; DOI=10.1167/iovs.12-11043
Koji Kitazawa, Satoshi Kawasaki, Katsuhiko Shinomiya, Keita Aoi, Akira Matsuda, Toshinari Funaki, Kenta Yamasaki, Mina Nakatsukasa, Nobuyuki Ebihara, Akira Murakami, Junji Hamuro, Shigeru Kinoshita;
Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy.
Invest. Ophthalmol. Vis. Sci. 54:5701-5711(2013)

Cross-references
Encyclopedic resources Wikidata; Q54897563
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number16