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Cellosaurus LPS3 (CVCL_SA56)

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Cell line name LPS3
Synonyms LP3
Accession CVCL_SA56
Resource Identification Initiative To cite this cell line use: LPS3 (RRID:CVCL_SA56)
Comments Characteristics: Derived from LPSX3, a mouse xenograft of a transplanted human liposarcoma.
Omics: Metabolomics.
Omics: Variations; SNP array analysis.
Disease Dedifferentiated liposarcoma (NCIt: C3704)
Dedifferentiated liposarcoma (ORDO: Orphanet_99970)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=23230188; DOI=10.1158/2159-8290.CD-12-0197; PMCID=PMC3531869
Daniel Braas, Ethan Ahler, Brenna M. Tam, David Nathanson, Mireille Riedinger, Matthias R. Benz, Kathleen B. Smith, Fritz C. Eilber, Owen Neil Witte, William Douglas Tap, Hong Wu, Heather R. Christofk;
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment.
Cancer Discov. 2:1109-1117(2012)

PubMed=23416162; DOI=10.1016/j.ajpath.2013.01.002; PMCID=PMC3620414
Kathleen B. Smith, Linh M. Tran, Brenna M. Tam, Elizabeth M. Shurell, Yun-Feng Li, Daniel Braas, William Douglas Tap, Heather R. Christofk, Sarah M. Dry, Fritz C. Eilber, Hong Wu;
Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibition.
Am. J. Pathol. 182:1400-1411(2013)

PubMed=26643872; DOI=10.18632/oncotarget.6464; PMCID=PMC4767443
Deepika Kanojia, Yasunobu Nagata, Manoj Garg, Dhong Hyun Lee, Aiko Sato, Kenichi Yoshida, Yusuke Sato, Masashi Sanada, Anand Mayakonda, Christoph Bartenhagen, Hans-Ulrich Klein ...Show all 28 authors... , Ngan B. Doan, Jonathan William Said, S. Mohith, Swetha Gunasekar, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ola Myklebost, Henry He Yang, Martin Dugas, Leonardo Andres Meza-Zepeda, Allan W. Silberman, Charles Forscher, Jeffrey W. Tyner, Seishi Ogawa, Harold Phillip Koeffler; Show fewer authors
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cross-references
Encyclopedic resources Wikidata; Q54902993
Polymorphism and mutation databases Cosmic; 2800526
Entry history
Entry creation14-May-2018
Last entry update10-Apr-2025
Version number6