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Cellosaurus HKCI-7 (CVCL_SA05)

[Text version]
Cell line name HKCI-7
Accession CVCL_SA05
Resource Identification Initiative To cite this cell line use: HKCI-7 (RRID:CVCL_SA05)
Comments Population: Chinese.
Virology: Expresses chimeric hepatitis B virus (HBV)-human transcripts (PubMed=24582836).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=19003983; DOI=10.1002/ijc.23968
Wong N., Yeo W., Wong W.-L., Wong N.L.-Y., Chan K.Y.-Y., Mo F.K.-F., Koh J., Chan S.L., Chan A.T.-C., Lai P.B.-S., Ching A.K.-K., Tong J.H.-M., Ng H.-K., Johnson P.J., To K.-F.
TOP2A overexpression in hepatocellular carcinoma correlates with early age onset, shorter patients survival and chemoresistance.
Int. J. Cancer 124:644-652(2009)

PubMed=24582836; DOI=10.1016/j.ccr.2014.01.030
Lau C.-C., Sun T.-T., Ching A.K.-K., He M., Li J.-W., Wong A.M., Co N.N., Chan A.W.-H., Li P.-S., Lung R.W.-M., Tong J.H.-M., Lai P.B.-S., Chan H.L.-Y., To K.-F., Chan T.-F., Wong N.
Viral-human chimeric transcript predisposes risk to liver cancer development and progression.
Cancer Cell 25:335-349(2014)

Cross-references
Encyclopedic resources Wikidata; Q54889759
Entry history
Entry creation14-May-2018
Last entry update10-Apr-2025
Version number9