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Cellosaurus HPDE-4/E6E7 (CVCL_S974)

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Cell line name HPDE-4/E6E7
Synonyms HPDE4/E6E7; HPDE4; Human Pancreatic Duct Epithelial-4 E6E7 immortalized
Accession CVCL_S974
Resource Identification Initiative To cite this cell line use: HPDE-4/E6E7 (RRID:CVCL_S974)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Proteomics; 2DE-MS.
Donor information: Established from a patient suffering from acute and chronic pancreatitis.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Pancreatic ductal cell; CL=CL_0002079.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Transformed cell line
Publications

PubMed=8669463; PMCID=PMC1861644
Toru Furukawa, William Paris Duguid, Lawrence Rosenberg, Jean Viallet, Denise A. Galloway, Ming-Sound Tsao;
Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.
Am. J. Pathol. 148:1763-1770(1996)

DOI=10.4172/jpb.1000057
Masayo Yamada, Kiyonaga Fujii, Koji Koyama, Setsuo Hirohashi, Tadashi Kondo;
The proteomic profile of pancreatic cancer cell lines corresponding to carcinogenesis and metastasis.
J. Proteomics Bioinformatics 2:1-18(2009)

Cross-references
Encyclopedic resources Wikidata; Q54890281
Entry history
Entry creation03-Feb-2014
Last entry update14-Aug-2025
Version number17