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Cellosaurus H2T (CVCL_S971)

[Text version]
Cell line name H2T
Accession CVCL_S971
Resource Identification Initiative To cite this cell line use: H2T (RRID:CVCL_S971)
Comments Doubling time: 24-28 hours (PubMed=7089870).
Transformant: ChEBI; CHEBI_140063; N-nitrobis(2-hydroxypropyl)amine (BHP).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; UniProtKB; A0A1U7QTX5; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Unspecified (PubMed=7809022).
Disease Hamster pancreatic ductal adenocarcinoma (NCIt: C133090)
Species of origin Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=7089870
Townsend C.M. Jr., Franklin R.B., Gelder F.B., Glass E., Thompson J.C.
Development of a transplantable model of pancreatic duct adenocarcinoma.
Surgery 92:72-78(1982)

PubMed=1499946; DOI=10.5555/uri:pii:001650859290032T
Sumi S., Beauchamp R.D., Townsend C.M. Jr., Uchida T., Murakami M., Rajaraman S., Ishizuka J., Thompson J.C.
Inhibition of pancreatic adenocarcinoma cell growth by lovastatin.
Gastroenterology 103:982-989(1992)

PubMed=7809021; DOI=10.1097/00006676-199409000-00017
Farre A., Ishizuka J., Gomez G., Evers B.M., Saydjari R., Koo J.Y., Townsend C.M. Jr., Thompson J.C.
Bombesin inhibits growth of pancreatic ductal adenocarcinoma (H2T) in nude mice.
Pancreas 9:652-656(1994)

PubMed=7809022; DOI=10.1097/00006676-199409000-00018
Sumi S., Beauchamp R.D., Townsend C.M. Jr., Pour P.M., Ishizuka J., Thompson J.C.
Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation.
Pancreas 9:657-661(1994)

PubMed=8863680; PMCID=PMC1865186
Erill N., Cuatrecasas M., Sancho F.J., Farre A., Pour P.M., Lluis F., Capella G.
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
Am. J. Pathol. 149:1333-1339(1996)

Cross-references
Encyclopedic resources Wikidata; Q54872049
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number13