Cellosaurus cell line HSC-GRW (CVCL

Cross-references
Cell line name	HSC-GRW
Accession	CVCL_S965
Resource Identification Initiative	To cite this cell line use: HSC-GRW (RRID:CVCL_S965)
Comments	Characteristics: KITLG dependent.
Sequence variations	Mutation; HGNC; HGNC:4170; GATA1; Simple; p.Pro50fs*6 (c.150_184del35); Zygosity=Unspecified (PubMed=12586620).
Disease	Down syndrome (NCIt: C2993) Myeloid leukemia associated with Down syndrome (NCIt: C43223) Down syndrome (ORDO: Orphanet_870) Acute megakaryoblastic leukemia in Down syndrome (ORDO: Orphanet_99887)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	CLPUB00052 Alvin Zipursky, Wilma Vanek, Tom Grunberger, Elizabeth J. Brown, Hong Wang, D. Robert Sutherland, Erik Logan Yeo, Amos Cohen, Hilary Christensen, Melvin Harris Freedman; A megakaryoblast cell line from a patient with Down syndrome-acute megakaryoblastic leukemia (DS-AMKL): in vitro differentiation of megakaryoblasts. Blood 82 Suppl. 1:122a.474-122a.474(1993) PubMed=12586620; DOI=10.1182/blood-2003-01-0013 Johann K. Hitzler, Joseph Cheung, Yue Li, Stephen Wayne Scherer, Alvin Zipursky; GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood 101:4301-4304(2003)
Encyclopedic resources	Wikidata; Q54896415
Polymorphism and mutation databases	Cosmic; 977943
Entry history
Entry creation	03-Feb-2014
Last entry update	19-Dec-2024
Version number	10