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Cellosaurus C146 (CVCL_S958)

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Cell line name C146
Accession CVCL_S958
Resource Identification Initiative To cite this cell line use: C146 (RRID:CVCL_S958)
Comments Doubling time: 16 +- 1 hours (PubMed=3947514).
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Disease Colorectal adenocarcinoma (NCIt: C5105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX
CSF1PO12
D5S81813
D7S82010,12
D13S3178,11
D16S53912,13
D21S1129,32.2
TH017,9.3
TPOX8,11
vWA14,18,19

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Publications

PubMed=3947514; DOI=10.1038/bjc.1986.6; PMCID=PMC2001479
Lindy G. Durrant, Richard Adrian Robins, Malcolm V. Pimm, Alan C. Perkins, Nicholas C.M. Armitage, Jack Donald Hardcastle, Robert W. Baldwin;
Antigenicity of newly established colorectal carcinoma cell lines.
Br. J. Cancer 53:37-45(1986)

PubMed=3435698; DOI=10.1038/bjc.1987.277; PMCID=PMC2002417
Lindy G. Durrant, Mathew C. Garnett, J. Gallego, Nicholas C.M. Armitage, Kenneth C. Ballantyne, Ruth A. Marksman, Jack Donald Hardcastle, Robert W. Baldwin;
Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.
Br. J. Cancer 56:722-726(1987)

PubMed=1846553; DOI=10.1038/bjc.1991.14; PMCID=PMC1971664
Lindy G. Durrant, Susan A. Watson, A. Hall, David Lawson Morris;
Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor alpha and insulin like growth factor-I.
Br. J. Cancer 63:67-70(1991)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Encyclopedic resources Wikidata; Q54807857
Gene expression databases GEO; GSM1448198
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number11