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Cellosaurus C146 (CVCL_S958)

[Text version]
Cell line name C146
Accession CVCL_S958
Resource Identification Initiative To cite this cell line use: C146 (RRID:CVCL_S958)
Comments Doubling time: 16 +- 1 hours (PubMed=3947514).
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Disease Colorectal adenocarcinoma (NCIt: C5105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX
CSF1PO12
D5S81813
D7S82010,12
D13S3178,11
D16S53912,13
D21S1129,32.2
TH017,9.3
TPOX8,11
vWA14,18,19

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Publications

PubMed=3947514; DOI=10.1038/bjc.1986.6; PMCID=PMC2001479
Durrant L.G., Robins R.A., Pimm M.V., Perkins A.C., Armitage N.C.M., Hardcastle J.D., Baldwin R.W.
Antigenicity of newly established colorectal carcinoma cell lines.
Br. J. Cancer 53:37-45(1986)

PubMed=3435698; DOI=10.1038/bjc.1987.277; PMCID=PMC2002417
Durrant L.G., Garnett M.C., Gallego J., Armitage N.C.M., Ballantyne K.C., Marksman R.A., Hardcastle J.D., Baldwin R.W.
Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.
Br. J. Cancer 56:722-726(1987)

PubMed=1846553; DOI=10.1038/bjc.1991.14; PMCID=PMC1971664
Durrant L.G., Watson S.A., Hall A., Morris D.L.
Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor alpha and insulin like growth factor-I.
Br. J. Cancer 63:67-70(1991)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Encyclopedic resources Wikidata; Q54807857
Gene expression databases GEO; GSM1448198
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number11