Cellosaurus cell line FD-LSC-1 (CVCL

Cross-references
Cell line name	FD-LSC-1
Accession	CVCL_S891
Resource Identification Initiative	To cite this cell line use: FD-LSC-1 (RRID:CVCL_S891)
Comments	Population: Chinese. Characteristics: Highly tumorigenic in NOD/SCID mice. Doubling time: 24 hours (PubMed=24001612). Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val173Leu (c.517G>T); ClinVar=VCV000376668; Zygosity=Unspecified (PubMed=24001612). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (PubMed=24001612).
Disease	Laryngeal squamous cell carcinoma (NCIt: C4044) Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	68Y
Category	Cancer cell line
Publications	PubMed=24001612; DOI=10.1016/j.canlet.2013.08.041 Chun-Ping Wu, Liang Zhou, Hong-Li Gong, Huai-Dong Du, Jie Tian, Shan Sun, Jin-Yan Li; Establishment and characterization of a novel HPV-negative laryngeal squamous cell carcinoma cell line, FD-LSC-1, with missense and nonsense mutations of TP53 in the DNA-binding domain. Cancer Lett. 342:92-103(2014)
Cell line databases/resources	cancercelllines; CVCL_S891
Encyclopedic resources	Wikidata; Q54833431
Entry history
Entry creation	03-Feb-2014
Last entry update	19-Dec-2024
Version number	13