Cellosaurus logo
expasy logo

Cellosaurus HROC24 (CVCL_S853)

[Text][XML][JSON]
Cell line name HROC24
Synonyms HROC24P
Accession CVCL_S853
Resource Identification Initiative To cite this cell line use: HROC24 (RRID:CVCL_S853)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
HLA typing Source: Direct_author_submission
Class I
HLA-AA*02:01,30:02
HLA-BB*18:01,38:01
HLA-CC*05:01,12:03
Class II
HLA-DQDQB1*02:01,06:01
HLA-DRDRB1*03:01,13:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YD57 ! B-LCL-HROC24
CVCL_1U80 ! HROC24 T1 M1
CVCL_AN14 ! HROC24 T3 M1 #2
Sex of cell Male
Age at sampling 98Y
Category Cancer cell line
STR profile Source(s): CLS=300812; Direct_author_submission; PubMed=25926053

Markers:
AmelogeninX,Y
CSF1PO10,11 (Direct_author_submission)
11,12 (CLS=300812; PubMed=25926053)
D5S81810,11 (CLS=300812; PubMed=25926053)
10,12 (Direct_author_submission)
D7S82011,13
D13S3177 (Direct_author_submission)
7,13 (CLS=300812; PubMed=25926053)
D16S5399,11
D21S1127,28
TH016,9
TPOX11
vWA16,20 (CLS=300812; PubMed=25926053)
16,21 (Direct_author_submission)

Run an STR similarity search on this cell line
Publications

PubMed=23300683; DOI=10.1371/journal.pone.0052485; PMCID=PMC3534085
Claudia Maletzki, Saskia Stier, Ulrike Gruenert, Michael Gock, Christiane Ostwald, Friedrich Prall, Michael Linnebacher;
Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas.
PLoS ONE 7:e52485.1-e52485.12(2012)

PubMed=25309914; DOI=10.1155/2014/568693; PMCID=PMC4182691
Falko Lange, Benjamin Franz, Claudia Maletzki, Michael Linnebacher, Maja Huhns, Robert Jaster;
Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
BioMed Res. Int. 2014:568693.1-568693.13(2014)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Christina Susanne Mullins, Bianca Micheel, Stephanie Matschos, Matthias Leuchter, Florian Burtin, Mathias Krohn, Maja Huhns, Ernst Klar, Friedrich Prall, Michael Linnebacher;
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300812
Encyclopedic resources Wikidata; Q54895254
Gene expression databases GEO; GSM1448071
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number23